| Gene Information | |
|---|---|
| Gene Name | DENR |
| Organism | Homo sapiens (Human) |
| Gene Length | 198 |
| Protein Names | Density-regulated protein (DRP) (Protein DRP1) (Smooth muscle cell-associated protein 3) (SMAP-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139726 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43583 |
| Gene Card | DENR |
| Uniprot ID | O43583 |
| Pfam | PF01253 |
| In ASD | no |
| Allosteric Prediction | no (-0.929638103) |
| Ortholog in Animals | Alpaca_ DENR ( ortholog_one2one ) Dog_ DENR ( ortholog_one2one ) GuineaPig_ DENR ( ortholog_one2one ) Macaque_ DENR ( ortholog_one2one ) Mouse_ Denr ( ortholog_one2one ) Pig_ DENR ( ortholog_one2one ) Rat_ Denr ( ortholog_one2one ) Rabbit_ DENR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney. {ECO:0000269|PubMed:9628587}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.012766(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5ONS (X-ray 2.14A ) 5VYC (X-ray 6.00A ) 6MS4 (X-ray 2.00A ) 6VPQ (X-ray 1.74A ) 6VPR (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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