| Gene Information | |
|---|---|
| Gene Name | CFAP45 |
| Organism | Homo sapiens (Human) |
| Gene Length | 551 |
| Protein Names | Cilia- and flagella-associated protein 45 (Coiled-coil domain-containing protein 19) (Nasopharyngeal epithelium-specific protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000213085 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UL16 |
| Gene Card | CFAP45 |
| Uniprot ID | Q9UL16 |
| Pfam | PF13868 |
| In ASD | no |
| Allosteric Prediction | no (-1.631983453) |
| Ortholog in Animals | Alpaca_ CFAP45 ( ortholog_one2one ) Dog_ CFAP45 ( ortholog_one2one ) GuineaPig_ CFAP45 ( ortholog_one2one ) Macaque_ CFAP45 ( ortholog_one2one ) Mouse_ Cfap45 ( ortholog_one2one ) Pig_ CFAP45 ( ortholog_one2one ) Rat_ Cfap45 ( ortholog_one2one ) Rabbit_ CFAP45 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis, oviduct, medulla.oblongata |
| Tissue Specificity | Expressed in respiratory cells and in sperm (at protein level) (PubMed:33139725). Expressed in nasopharyngeal epithelium and trachea (PubMed:10524255). {ECO:0000269|PubMed:10524255, ECO:0000269|PubMed:33139725}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16842789 rs201144590 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:33139725}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000269|PubMed:33139725}. Note=Located in the proximal region of respiratory cilia. {ECO:0000269|PubMed:33139725}. |
| Mouse PG classification | NA |
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