| Gene Information | |
|---|---|
| Gene Name | CFAP410 |
| Organism | Homo sapiens (Human) |
| Gene Length | 256 |
| Protein Names | Cilia- and flagella-associated protein 410 (C21orf-HUMF09G8.5) (Leucine-rich repeat-containing protein 76) (YF5/A2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000160226 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43822 |
| Gene Card | CFAP410 |
| Uniprot ID | O43822 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.222442553) |
| Ortholog in Animals | Alpaca_ CFAP410 ( ortholog_one2one ) Dog_ ICOSLG ( ortholog_one2one ) GuineaPig_ CFAP410 ( ortholog_one2one ) Macaque_ CFAP410 ( ortholog_one2one ) Mouse_ Cfap410 ( ortholog_one2one ) Pig_ CFAP410 ( ortholog_one2one ) Rat_ Cfap410 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (PubMed:26974433, PubMed:9325172). Expressed in the retina (PubMed:26294103). |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1057518441 rs140451304 rs1131690801 rs763623409 rs555164150 rs922930539 rs2277809 rs9306099 rs1114167892 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:9325172}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:26167768, ECO:0000269|PubMed:26294103}. Cell projection, cilium, photoreceptor outer segment {ECO:0000269|PubMed:27548899}. Cytoplasm {ECO:0000269|PubMed:26290490}. Note=Colocalizes with NEK1 and SPATA7 at the basal body. {ECO:0000269|PubMed:26167768}. |
| Mouse PG classification | NA |
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