Gene Information
Gene NameCES1
OrganismHomo sapiens (Human)
Gene Length61
Protein NamesMetallothionein-2 (MT-2) (Metallothionein-2A) (Metallothionein-II) (MT-II)
Target Nameliver carboxylesterase
Target TypeSuccessful target
Gene Age1064 ( ENSG00000198848 )
3 ( ENSG00000262243 )
Evolutionary StageEumetazoa
AlphaFoldDBP02795
Gene CardMT2A
Uniprot IDP02795
PfamPF00131
In ASDno
Allosteric Predictionyes (0.778909321)
Ortholog in AnimalsAlpaca_ CES1 ( ortholog_one2one )
Macaque_ CES1 ( ortholog_one2one )
Mouse_ Ces1g ( ortholog_one2many )
Mouse_ Ces1h ( ortholog_one2many )
Mouse_ Ces1c ( ortholog_one2many )
Mouse_ Ces1b ( ortholog_one2many )
Mouse_ Ces1d ( ortholog_one2many )
Pig_ CES1 ( ortholog_one2one )
Rat_ Cesl1 ( ortholog_one2many )
Rat_ Ces1d ( ortholog_one2many )
OhnologsNA
ParalogsNLGN2, ACHE, NLGN4X, NLGN4Y, CES3, NLGN1, CES2, CES5A, CES4A, BCHE, TG, NLGN3, CEL
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1MHU  (NMR  2MHU  (NMR 
DBSNP rs35109646 
Subcellular location [CC]NA
Mouse PG classificationNA
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