| Gene Information | |
|---|---|
| Gene Name | CES1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 61 |
| Protein Names | Metallothionein-2 (MT-2) (Metallothionein-2A) (Metallothionein-II) (MT-II) |
| Target Name | liver carboxylesterase |
| Target Type | Successful target |
| Gene Age | 1064 ( ENSG00000198848 ) 3 ( ENSG00000262243 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P02795 |
| Gene Card | MT2A |
| Uniprot ID | P02795 |
| Pfam | PF00131 |
| In ASD | no |
| Allosteric Prediction | yes (0.778909321) |
| Ortholog in Animals | Alpaca_ CES1 ( ortholog_one2one ) Macaque_ CES1 ( ortholog_one2one ) Mouse_ Ces1g ( ortholog_one2many ) Mouse_ Ces1h ( ortholog_one2many ) Mouse_ Ces1c ( ortholog_one2many ) Mouse_ Ces1b ( ortholog_one2many ) Mouse_ Ces1d ( ortholog_one2many ) Pig_ CES1 ( ortholog_one2one ) Rat_ Cesl1 ( ortholog_one2many ) Rat_ Ces1d ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NLGN2, ACHE, NLGN4X, NLGN4Y, CES3, NLGN1, CES2, CES5A, CES4A, BCHE, TG, NLGN3, CEL |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1MHU (NMR - ) 2MHU (NMR - ) |
| DBSNP | rs35109646 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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