| Gene Information | |
|---|---|
| Gene Name | CERS6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Ceramide synthase 6 (CerS6) (LAG1 longevity assurance homolog 6) (Sphingoid base N-palmitoyltransferase CERS6) (EC 2.3.1.291) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000172292 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ZMG9 |
| Gene Card | CERS6 |
| Uniprot ID | Q6ZMG9 |
| Pfam | PF00046; PF03798 |
| In ASD | no |
| Allosteric Prediction | no (-0.999826059) |
| Ortholog in Animals | Alpaca_ CERS6 ( ortholog_one2one ) Dog_ CERS6 ( ortholog_one2one ) GuineaPig_ CERS6 ( ortholog_one2one ) Macaque_ CERS6 ( ortholog_one2one ) Mouse_ Cers6 ( ortholog_one2one ) Pig_ CERS6 ( ortholog_one2one ) Rat_ Cers6 ( ortholog_one2one ) Rabbit_ CERS6 ( ortholog_one2one ) |
| Ohnologs | CERS5 |
| Paralogs | CERS5, CERS3, CERS4, CERS2, CERS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8C172}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8C172}. |
| Mouse PG classification | NA |
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