Gene Information
Gene NameCERS4
OrganismHomo sapiens (Human)
Gene Length394
Protein NamesCeramide synthase 4 (CerS4) (EC 2.3.1.-) (LAG1 longevity assurance homolog 4) (Sphingosine N-acyltransferase CERS4) (EC 2.3.1.24)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000090661 )
Evolutionary StageEukaryota
AlphaFoldDBQ9HA82
Gene CardCERS4
Uniprot IDQ9HA82
PfamPF00046; PF03798
In ASDno
Allosteric Predictionno (-0.347825111)
Ortholog in AnimalsAlpaca_ CERS4 ( ortholog_one2one )
Dog_ CERS4 ( ortholog_one2one )
GuineaPig_ CERS4 ( ortholog_one2one )
Macaque_ CERS4 ( ortholog_one2one )
Mouse_ Cers4 ( ortholog_one2one )
Pig_ CERS4 ( ortholog_one2one )
Rat_ Cers4 ( ortholog_one2one )
Rabbit_ CERS4 ( ortholog_one2one )
OhnologsCERS2, CERS3
ParalogsCERS3, CERS2, CERS5, CERS6, CERS1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs17159388  rs2288413  rs17160348  rs36259  rs17160349 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9D6J1};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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