Gene Information | |
---|---|
Gene Name | CERP |
Organism | Homo sapiens (Human) |
Gene Length | 2261 |
Protein Names | Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | O95477 |
Gene Card | ABCA1 |
Uniprot ID | O95477 |
Pfam | PF00005 |
In ASD | yes |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Widely expressed, but most abundant in macrophages. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 5XJY (EM 4.10A ) 7ROQ (EM 4.10A ) |
DBSNP | rs145183203 rs2230806 rs9282541 rs142625938 rs758100110 rs775035559 rs9282543 rs138487227 rs147675550 rs2853574 rs137854496 rs137854496 rs2853578 rs374190304 rs2066718 rs35819696 rs138880920 rs145582736 rs2066715 rs1322998567 rs2066714 rs28937314 rs28937313 rs137854495 rs141021096 rs13306072 rs745593394 rs28933692 rs33918808 rs76881554 rs562403512 rs137854500 rs147743782 rs145689805 rs189206655 rs137854494 rs137854497 rs1997618 rs2230808 rs1251839800 rs1883024 rs1203589782 rs150125857 rs137854498 rs760507032 rs146292819 rs1055285452 rs760768125 rs142688906 rs137854499 rs137854501 rs369098049 rs2853577 rs564764153 rs34879708 rs144588452 |
Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19258317, ECO:0000269|PubMed:19556522, ECO:0000269|PubMed:24097981}; Multi-pass membrane protein {ECO:0000305|PubMed:19258317}. Endosome {ECO:0000269|PubMed:24097981}. |
Mouse PG classification | NA |
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