| Gene Information | |
|---|---|
| Gene Name | ELFN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 828 |
| Protein Names | Protein ELFN1 (Extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1) (Protein phosphatase 1 regulatory subunit 28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000225968 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P0C7U0 |
| Gene Card | ELFN1 |
| Uniprot ID | P0C7U0 |
| Pfam | PF13855 |
| In ASD | no |
| Allosteric Prediction | no (-0.809244035) |
| Ortholog in Animals | Alpaca_ ELFN1 ( ortholog_one2one ) Dog_ ELFN1 ( ortholog_one2one ) GuineaPig_ ELFN1 ( ortholog_one2one ) Macaque_ ELFN1 ( ortholog_one2one ) Mouse_ Elfn1 ( ortholog_one2one ) Pig_ ELFN1 ( ortholog_one2one ) Rat_ Elfn1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRG1, CPN2, LRRTM2, LRRC52, LRIT3, LRRC24, ELFN2, LRIG3, LGR6, LGR5, CHAD, CHADL, LRIT1, TRIL, LGR4, LGI2, LGI1, LRIG2, LRRC26, LRIG1, LGI3, LGI4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Cell projection, dendrite {ECO:0000250}. Note=Localizes to excitatory synapses onto somatostatin (Sst)-containing oriens-lacunosum moleculare (O-LM) interneurons. {ECO:0000250}. |
| Mouse PG classification | NA |
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