| Gene Information | |
|---|---|
| Gene Name | CEP19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 163 |
| Protein Names | Centrosomal protein of 19 kDa (Cep19) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000174007 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96LK0 |
| Gene Card | CEP19 |
| Uniprot ID | Q96LK0 |
| Pfam | PF14933 |
| In ASD | no |
| Allosteric Prediction | no (-1.273073834) |
| Ortholog in Animals | Alpaca_ CEP19 ( ortholog_one2one ) GuineaPig_ CEP19 ( ortholog_one2one ) Macaque_ CEP19 ( ortholog_one2one ) Mouse_ Cep19 ( ortholog_one2one ) Pig_ CEP19 ( ortholog_one2one ) Rat_ Cep19 ( ortholog_one2one ) Rabbit_ CEP19 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:28428259, ECO:0000269|PubMed:28625565, ECO:0000269|PubMed:28659385}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:21399614}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:24268657, ECO:0000269|PubMed:28428259, ECO:0000269|PubMed:28625565, ECO:0000269|PubMed:28659385}. Note=Associates with the mother centriole in early interphase. Localizes to spindle poles during mitosis, and to distinct foci oriented towards the midbody at telophase (PubMed:21399614). Localizes slightly apical to the subdistal appendage on the mother centriole, but below the distal appendage (PubMed:28625565, PubMed:28659385). {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:28625565}. |
| Mouse PG classification | NA |
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