| Gene Information | |
|---|---|
| Gene Name | CEP104 |
| Organism | Homo sapiens (Human) |
| Gene Length | 925 |
| Protein Names | Centrosomal protein of 104 kDa (Cep104) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000116198 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60308 |
| Gene Card | CEP104 |
| Uniprot ID | O60308 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.784641988) |
| Ortholog in Animals | Alpaca_ CEP104 ( ortholog_one2one ) Dog_ CEP104 ( ortholog_one2one ) GuineaPig_ CEP104 ( ortholog_one2one ) Macaque_ CEP104 ( ortholog_one2one ) Mouse_ Cep104 ( ortholog_one2one ) Pig_ CEP104 ( ortholog_one2one ) Rat_ Cep104 ( ortholog_one2one ) Rabbit_ CEP104 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5LPH (X-ray 2.25A ) 5LPI (X-ray 1.80A ) |
| DBSNP | rs2275824 rs2275831 |
| Subcellular location [CC] | Cell projection, cilium {ECO:0000269|PubMed:23970417}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:21399614, ECO:0000269|PubMed:23970417}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23970417}. Cytoplasm, cytoskeleton, spindle pole. Note=In interphase non-ciliated cells, localizes to the distal ends of both the mother and daughter centrioles. In ciliated cells, present at the distal end of the daughter centriole, but not on the mother centriole, and at the tip of primary cilium. Localization at the ciliary tip is also observed in motile cilia. Throughout S phase, associated with both mother and daughter centrioles in each centrosome. During metaphase and telophase, present at both spindle poles. {ECO:0000269|PubMed:23970417}. |
| Mouse PG classification | NA |
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