| Gene Information | |
|---|---|
| Gene Name | DUSP10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 482 |
| Protein Names | Dual specificity protein phosphatase 10 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000143507 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y6W6 |
| Gene Card | DUSP10 |
| Uniprot ID | Q9Y6W6 |
| Pfam | PF00782; PF00581 |
| In ASD | yes |
| Allosteric Prediction | no (-0.658471482) |
| Ortholog in Animals | Alpaca_ DUSP10 ( ortholog_one2one ) Dog_ DUSP10 ( ortholog_one2one ) GuineaPig_ DUSP10 ( ortholog_one2one ) Macaque_ DUSP10 ( ortholog_one2one ) Mouse_ Dusp10 ( ortholog_one2one ) Pig_ DUSP10 ( ortholog_one2one ) Rat_ Dusp10 ( ortholog_one2one ) Rabbit_ DUSP10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DUSP6, DUSP4, DUSP12, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9, DUSP3 |
| Tissue | NA |
| Tissue Specificity | Expressed in keratinocytes (at protein level) (PubMed:29043977). Detected in brain (PubMed:16806267). {ECO:0000269|PubMed:16806267, ECO:0000269|PubMed:29043977}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ZZW (X-ray 1.60A ) 2OUC (X-ray 2.20A ) 2OUD (X-ray 2.80A ) 3TG1 (X-ray 2.71A ) 6MC1 (X-ray 2.70A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Nucleus. |
| Mouse PG classification | NA |
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