| Gene Information | |
|---|---|
| Gene Name | CELSR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3312 |
| Protein Names | Cadherin EGF LAG seven-pass G-type receptor 3 (Cadherin family member 11) (Epidermal growth factor-like protein 1) (EGF-like protein 1) (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains protein 2) (Multiple EGF-like domains protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000008300 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | CELSR3 |
| Uniprot ID | Q9NYQ7 |
| Pfam | PF00002; PF00028; PF00008; PF16489; PF01825; PF00053; PF02210 |
| In ASD | no |
| Allosteric Prediction | no (-0.881951061) |
| Ortholog in Animals | Alpaca_ CELSR3 ( ortholog_one2one ) Dog_ CELSR3 ( ortholog_one2one ) GuineaPig_ CELSR3 ( ortholog_one2one ) Macaque_ CELSR3 ( ortholog_one2one ) Mouse_ Celsr3 ( ortholog_one2one ) Pig_ CELSR3 ( ortholog_one2one ) Rat_ Celsr3 ( ortholog_one2one ) Rabbit_ CELSR3 ( ortholog_one2one ) |
| Ohnologs | CELSR1, CELSR2 |
| Paralogs | FAT2, FAT1, CELSR1, FAT4, FAT3, CELSR2 |
| Tissue | cerebellar.hemisphere, cerebellum, pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3733085 rs3821875 rs12107252 rs587777163 rs149614835 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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