| Gene Information | |
|---|---|
| Gene Name | SYNGR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 224 |
| Protein Names | Synaptogyrin-2 (Cellugyrin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000108639 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O43760 |
| Gene Card | SYNGR2 |
| Uniprot ID | O43760 |
| Pfam | PF01284 |
| In ASD | no |
| Allosteric Prediction | no (-0.604960494) |
| Ortholog in Animals | Dog_ SYNGR2 ( ortholog_one2one ) GuineaPig_ SYNGR2 ( ortholog_one2one ) Macaque_ SYNGR2 ( ortholog_one2one ) Mouse_ Syngr2 ( ortholog_one2one ) Pig_ SYNGR2 ( ortholog_one2one ) Rat_ Syngr2 ( ortholog_one2one ) |
| Ohnologs | SYNGR1, SYNGR3 |
| Paralogs | SYNGR1, SYNGR3, SYNGR4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous; low expression in brain. {ECO:0000269|PubMed:9760194}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:O54980}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:O54980}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to cytoplasmic vesicles associated with the recycling endosomes. {ECO:0000250|UniProtKB:O54980}.; Lipid droplet. Note=(Microbial infection) Upon SFTS phlebovirus infection, the protein localizes in lipid droplets and inclusion bodies. {ECO:0000269|PubMed:27226560}. |
| Mouse PG classification | NA |
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