| Gene Information | |
|---|---|
| Gene Name | CELF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 486 |
| Protein Names | CUGBP Elav-like family member 1 (CELF-1) (50 kDa nuclear polyadenylated RNA-binding protein) (Bruno-like protein 2) (CUG triplet repeat RNA-binding protein 1) (CUG-BP1) (CUG-BP- and ETR-3-like factor 1) (Deadenylation factor CUG-BP) (Embryo deadenylation element-binding protein homolog) (EDEN-BP homolog) (RNA-binding protein BRUNOL-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000149187 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q92879 |
| Gene Card | CELF1 |
| Uniprot ID | Q92879 |
| Pfam | PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.228437886) |
| Ortholog in Animals | Alpaca_ CELF1 ( ortholog_one2one ) Dog_ CELF1 ( ortholog_one2one ) GuineaPig_ CELF1 ( ortholog_one2one ) Macaque_ CELF1 ( ortholog_one2one ) Mouse_ Celf1 ( ortholog_one2one ) Pig_ CELF1 ( ortholog_one2one ) Rat_ Celf1 ( ortholog_one2one ) Rabbit_ CELF1 ( ortholog_one2one ) |
| Ohnologs | CELF2 |
| Paralogs | CELF4, CELF2, RBM28, CELF3, CELF6, CELF5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:10893231, ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:16862542}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CPZ (NMR - ) 2DHS (NMR - ) 2RQ4 (NMR - ) 2RQC (NMR - ) 3NMR (X-ray 1.85A ) 3NNA (X-ray 1.90A ) 3NNC (X-ray 2.20A ) 3NNH (X-ray 2.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:8948631}. Cytoplasm {ECO:0000269|PubMed:8948631}. Note=RNA-binding activity is detected in both nuclear and cytoplasmic compartments. |
| Mouse PG classification | NA |
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