Gene Information
Gene NameCEL
OrganismHomo sapiens (Human)
Gene Length753
Protein NamesBile salt-activated lipase (BAL) (EC 3.1.1.13) (EC 3.1.1.3) (EC 3.1.1.6) (Bile salt-stimulated lipase) (BSSL) (Bucelipase) (Carboxyl ester lipase) (Cholesterol esterase) (Pancreatic lysophospholipase) (Sterol esterase)
Target Namebile salt-activated lipase
Target TypeNA
Gene Age645 ( ENSG00000170835 )
Evolutionary StageNA
AlphaFoldDBP19835
Gene CardCEL
Uniprot IDP19835
PfamPF00135; PF16058
In ASDno
Allosteric Predictionyes (0.434248413)
Ortholog in AnimalsGuineaPig_ CEL ( ortholog_one2one )
Macaque_ CEL ( ortholog_one2one )
Mouse_ Cel ( ortholog_one2one )
Pig_ CEL ( ortholog_one2one )
Rat_ Cel ( ortholog_one2one )
Rabbit_ CEL ( ortholog_one2one )
OhnologsNA
ParalogsNLGN2, ACHE, NLGN4X, NLGN4Y, CES3, NLGN1, CES2, CES5A, CES4A, BCHE, TG, NLGN3, CES1
Tissuepancreas
Tissue SpecificityMammary gland and pancreas. Detected in pancreatic and duodenal juice (at protein level) (PubMed:21784842). Expressed by eosinophils. {ECO:0000269|PubMed:11834744, ECO:0000269|PubMed:21784842}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1F6W  (X-ray  2.30A  1JMY  (X-ray  2.60A  6H0T  (X-ray  1.90A  6H0V  (X-ray  2.20A  6H18  (X-ray  1.85A  6H19  (X-ray  1.89A  6H1A  (X-ray  1.75A 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:21784842}.
Mouse PG classificationNA
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