Gene Information
Gene NameCHRNA9
OrganismHomo sapiens (Human)
Gene Length479
Protein NamesNeuronal acetylcholine receptor subunit alpha-9 (Nicotinic acetylcholine receptor subunit alpha-9) (NACHR alpha-9)
Target Nameneuronal acetylcholine receptor subunit alpha-9
Target TypeNA
Gene Age544 ( ENSG00000174343 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UGM1
Gene CardCHRNA9
Uniprot IDQ9UGM1
PfamPF02931; PF02932
In ASDno
Allosteric Predictionyes (0.768825278)
Ortholog in AnimalsAlpaca_ CHRNA9 ( ortholog_one2one )
Dog_ CHRNA9 ( ortholog_one2one )
GuineaPig_ CHRNA9 ( ortholog_one2one )
Macaque_ CHRNA9 ( ortholog_one2one )
Mouse_ Chrna9 ( ortholog_one2one )
Pig_ CHRNA9 ( ortholog_one2one )
Rat_ Chrna9 ( ortholog_one2one )
Rabbit_ CHRNA9 ( ortholog_one2one )
OhnologsCHRNA10
ParalogsCHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB
TissueNA
Tissue SpecificityExpressed in cochlea, keratinocytes, pituitary gland, B-cells and T-cells. {ECO:0000269|PubMed:11021840, ECO:0000269|PubMed:11752216, ECO:0000269|PubMed:15531379}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4D01  (X-ray  1.80A  )  4UXU  (X-ray  1.71A  )  4UY2  (X-ray  2.70A  )  6HY7  (X-ray  2.26A  ) 
DBSNP rs10024518  rs55633891  rs10009228 
Subcellular location [CC]Postsynaptic cell membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}. Cell membrane {ECO:0000269|PubMed:25282151};
Multi-pass membrane protein {ECO:0000305|PubMed:25282151}.
Mouse PG classificationNA
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