| Gene Information | |
|---|---|
| Gene Name | CEA |
| Organism | Homo sapiens (Human) |
| Gene Length | 702 |
| Protein Names | Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P06731 |
| Gene Card | CEACAM5 |
| Uniprot ID | P06731 |
| Pfam | PF13895; PF07686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. {ECO:0000269|PubMed:10436421}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1E07 (X-ray - ) 2QSQ (X-ray 1.95A ) 2QST (X-ray 2.90A ) 2VER (NMR - ) |
| DBSNP | rs12971352 rs28683503 rs3815780 rs10407503 rs7249230 rs10423171 rs9621 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10864933, ECO:0000269|PubMed:18086185, ECO:0000269|PubMed:2317824}; Lipid-anchor, GPI-anchor {ECO:0000269|PubMed:10864933, ECO:0000269|PubMed:18086185, ECO:0000269|PubMed:2317824}. Apical cell membrane {ECO:0000269|PubMed:10436421}. Cell surface {ECO:0000269|PubMed:2317824, ECO:0000269|PubMed:2803308}. Note=Localized to the apical glycocalyx surface. {ECO:0000269|PubMed:10436421}. |
| Mouse PG classification | NA |
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