Gene Information
Gene NameCDS1
OrganismHomo sapiens (Human)
Gene Length461
Protein NamesPhosphatidate cytidylyltransferase 1 (EC 2.7.7.41) (CDP-DAG synthase 1) (CDP-DG synthase 1) (CDP-diacylglycerol synthase 1) (CDS 1) (CDP-diglyceride pyrophosphorylase 1) (CDP-diglyceride synthase 1) (CTP:phosphatidate cytidylyltransferase 1)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000163624 )
Evolutionary StageEukaryota
AlphaFoldDBQ92903
Gene CardCDS1
Uniprot IDQ92903
PfamNA
In ASDno
Allosteric Predictionno (-0.740354328)
Ortholog in AnimalsAlpaca_ CDS1 ( ortholog_one2one )
Dog_ CDS1 ( ortholog_one2one )
GuineaPig_ CDS1 ( ortholog_one2one )
Macaque_ CDS1 ( ortholog_one2one )
Mouse_ Cds1 ( ortholog_one2one )
Pig_ CDS1 ( ortholog_one2one )
Rat_ Cds1 ( ortholog_one2one )
Rabbit_ CDS1 ( ortholog_one2one )
OhnologsCDS2
ParalogsCDS2
TissueNA
Tissue SpecificityExpressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver. {ECO:0000269|PubMed:9407135}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs36068434 
Subcellular location [CC]Endoplasmic reticulum membrane {ECO:0000269|PubMed:25375833, ECO:0000269|PubMed:26946540, ECO:0000269|PubMed:31548309};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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