Gene Information | |
---|---|
Gene Name | SMOX |
Organism | Homo sapiens (Human) |
Gene Length | 555 |
Protein Names | Spermine oxidase (EC 1.5.3.16) (Polyamine oxidase 1) (PAO-1) (PAOh1) |
Target Name | spermine oxidase |
Target Type | NA |
Gene Age | 1714 ( ENSG00000088826 ) |
Evolutionary Stage | Euk+Bac |
AlphaFoldDB | Q9NWM0 |
Gene Card | SMOX |
Uniprot ID | Q9NWM0 |
Pfam | PF01593 |
In ASD | yes |
Allosteric Prediction | yes (0.105885471) |
Ortholog in Animals | Alpaca_ SMOX ( ortholog_one2one ) Dog_ SMOX ( ortholog_one2one ) GuineaPig_ SMOX ( ortholog_one2one ) Macaque_ SMOX ( ortholog_one2one ) Mouse_ Smox ( ortholog_one2one ) Pig_ SMOX ( ortholog_one2one ) Rat_ RGD1564480 ( ortholog_one2many ) Rat_ Smox ( ortholog_one2many ) Rabbit_ SMOX ( ortholog_one2one ) |
Ohnologs | PAOX |
Paralogs | KDM1A, MAOA, PPOX, KDM1B, PAOX, MAOB, IL4I1 |
Tissue | NA |
Tissue Specificity | Widely expressed. Expressed in human tumor cell lines. Isoform 4 is only found in an embryonal kidney cell line. {ECO:0000269|PubMed:18422650}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 7OXL (X-ray 2.40A ) 7OY0 (X-ray 2.09A ) |
DBSNP | rs6084654 |
Subcellular location [CC] | [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 4]: Cytoplasm. Nucleus.; [Isoform 6]: Cytoplasm. Nucleus. |
Mouse PG classification | NA |
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