| Gene Information | |
|---|---|
| Gene Name | CPSF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 269 |
| Protein Names | Cleavage and polyadenylation specificity factor subunit 4 (Cleavage and polyadenylation specificity factor 30 kDa subunit) (CPSF 30 kDa subunit) (NS1 effector domain-binding protein 1) (Neb-1) (No arches homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000160917 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95639 |
| Gene Card | CPSF4 |
| Uniprot ID | O95639 |
| Pfam | PF00642; PF15663; PF00098 |
| In ASD | no |
| Allosteric Prediction | no (-0.655434924) |
| Ortholog in Animals | Alpaca_ CPSF4 ( ortholog_one2one ) Dog_ CPSF4 ( ortholog_one2one ) GuineaPig_ CPSF4 ( ortholog_one2one ) Macaque_ CPSF4 ( ortholog_one2one ) Mouse_ Cpsf4 ( ortholog_one2one ) Pig_ CPSF4 ( ortholog_one2one ) Rat_ AABR07037234.1 ( ortholog_one2one ) Rabbit_ CPSF4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CPSF4L, ZC3H3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002590(Rat);0.081868(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D9N (NMR - ) 2RHK (X-ray 1.95A ) 6DNH (EM 3.40A ) 6FBS 6FUW (EM 3.07A ) 6URG (EM 3.00A ) 6URO (EM 3.60A ) 7K95 (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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