| Gene Information | |
|---|---|
| Gene Name | TNIP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 429 |
| Protein Names | TNFAIP3-interacting protein 2 (A20-binding inhibitor of NF-kappa-B activation 2) (ABIN-2) (Fetal liver LKB1-interacting protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000168884 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NFZ5 |
| Gene Card | TNIP2 |
| Uniprot ID | Q8NFZ5 |
| Pfam | PF12180 |
| In ASD | no |
| Allosteric Prediction | no (-0.319779448) |
| Ortholog in Animals | Alpaca_ TNIP2 ( ortholog_one2one ) Dog_ TNIP2 ( ortholog_one2one ) Macaque_ TNIP2 ( ortholog_one2one ) Mouse_ Tnip2 ( ortholog_one2one ) Pig_ TNIP2 ( ortholog_one2one ) Rat_ Tnip2 ( ortholog_one2one ) Rabbit_ TNIP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TNIP3, TNIP1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed in all tissues examined. {ECO:0000269|PubMed:12595760}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.058824(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5H07 (X-ray 2.59A ) |
| DBSNP | rs116129895 rs116412781 rs2269495 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12595760}. Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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