| Gene Information | |
|---|---|
| Gene Name | CDK5RAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 601 |
| Protein Names | Mitochondrial tRNA methylthiotransferase CDK5RAP1 (EC 2.8.4.3) (CDK5 activator-binding protein C42) (CDK5 regulatory subunit-associated protein 1) (mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase) (mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000101391 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q96SZ6 |
| Gene Card | CDK5RAP1 |
| Uniprot ID | Q96SZ6 |
| Pfam | PF04055; PF01938; PF00919 |
| In ASD | no |
| Allosteric Prediction | no (-0.488649075) |
| Ortholog in Animals | Alpaca_ CDK5RAP1 ( ortholog_one2one ) Dog_ CDK5RAP1 ( ortholog_one2one ) GuineaPig_ CDK5RAP1 ( ortholog_one2one ) Macaque_ CDK5RAP1 ( ortholog_one2one ) Mouse_ Cdk5rap1 ( ortholog_one2one ) Pig_ CDK5RAP1 ( ortholog_one2one ) Rabbit_ CDK5RAP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDKAL1 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas (PubMed:10721722). Expressed in neurons of central nervous tissue (PubMed:10721722, PubMed:11882646). {ECO:0000269|PubMed:10721722, ECO:0000269|PubMed:11882646}.; [Isoform 5]: Mainly expressed in brain, placenta and testis.; [Isoform 6]: High expression in placenta and lung. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:22422838}. |
| Mouse PG classification | NA |
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