Gene Information
Gene NameANKH
OrganismHomo sapiens (Human)
Gene Length492
Protein NamesProgressive ankylosis protein homolog (ANK)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000154122 )
Evolutionary StageOpisthokonta
AlphaFoldDBQ9HCJ1
Gene CardANKH
Uniprot IDQ9HCJ1
PfamPF07260
In ASDno
Allosteric Predictionno (-0.815058963)
Ortholog in AnimalsAlpaca_ ANKH ( ortholog_one2one )
Dog_ ANKH ( ortholog_one2one )
GuineaPig_ ANKH ( ortholog_one2one )
Macaque_ ANKH ( ortholog_one2one )
Mouse_ Ank ( ortholog_one2one )
Pig_ ANKH ( ortholog_one2one )
Rat_ Ankh ( ortholog_one2one )
Rabbit_ ANKH ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityFound in osteoblasts from mandibular bone and from iliac bone;
not detected in osteoclastic cells.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs121908409  rs121908410  rs121908407  rs121908405  rs28939080  rs121908408 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}.
Mouse PG classificationHPG
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