| Gene Information | |
|---|---|
| Gene Name | CDHF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 999 |
| Protein Names | Desmoglein-3 (130 kDa pemphigus vulgaris antigen) (PVA) (Cadherin family member 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P32926 |
| Gene Card | DSG3 |
| Uniprot ID | P32926 |
| Pfam | PF00028 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Epidermis, tongue, tonsil, esophagus and carcinomas. Expressed in skin and mucosa (at protein level) (PubMed:30528827). {ECO:0000269|PubMed:30528827}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5EQX (X-ray 3.05A ) |
| DBSNP | rs16961975 rs1380866 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000255}. Cell junction, desmosome {ECO:0000305}. |
| Mouse PG classification | NA |
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