| Gene Information | |
|---|---|
| Gene Name | PLAC8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 139 |
| Protein Names | Galactoside-binding soluble lectin 13 (Galectin-13) (Gal-13) (Placental tissue protein 13) (PP13) (Placental protein 13) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000145287 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UHV8 |
| Gene Card | LGALS13 |
| Uniprot ID | Q9UHV8 |
| Pfam | PF00337 |
| In ASD | no |
| Allosteric Prediction | no (-0.742817453) |
| Ortholog in Animals | Alpaca_ PLAC8 ( ortholog_one2one ) Dog_ PLAC8B ( ortholog_one2one ) GuineaPig_ PLAC8 ( ortholog_one2one ) Macaque_ PLAC8 ( ortholog_one2one ) Mouse_ Plac8 ( ortholog_one2one ) Rat_ Plac8 ( ortholog_one2one ) Rabbit_ PLAC8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CNFN, PLAC8L1 |
| Tissue | spleen, transverse.colon, whole.blood |
| Tissue Specificity | Detected in adult and fetal spleen, fetal kidney, adult urinary bladder and placenta. Placental expression originates predominantly from the syncytiotrophoblast. {ECO:0000269|PubMed:10527825, ECO:0000269|PubMed:19497882}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XG7 (X-ray 1.55A ) 5XG8 (X-ray 1.55A ) 5Y03 (X-ray 2.12A ) 6A62 (X-ray 2.03A ) 6A63 (X-ray 1.63A ) 6A64 (X-ray 1.63A ) 6A65 (X-ray 1.77A ) 6A66 (X-ray 1.40A ) 6KJW (X-ray 1.36A ) 6KJX (X-ray 1.53A ) 6KJY (X-ray 1.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:29343868}. Nucleus matrix {ECO:0000269|PubMed:29343868}. |
| Mouse PG classification | NA |
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