Gene Information
Gene NameCDH22
OrganismHomo sapiens (Human)
Gene Length828
Protein NamesCadherin-22 (Pituitary and brain cadherin) (PB-cadherin)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000149654 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9UJ99
Gene CardCDH22
Uniprot IDQ9UJ99
PfamPF01049; PF00028
In ASDno
Allosteric Predictionno (-1.54899865)
Ortholog in AnimalsAlpaca_ CDH22 ( ortholog_one2one )
Dog_ CDH22 ( ortholog_one2one )
GuineaPig_ CDH22 ( ortholog_one2one )
Macaque_ CDH22 ( ortholog_one2one )
Mouse_ Cdh22 ( ortholog_one2one )
Pig_ CDH22 ( ortholog_one2one )
Rat_ Cdh22 ( ortholog_one2one )
OhnologsCDH1, CDH10, CDH3, CDH19, CDH7, CDH20, CDH9, CDH6, CDH15, CDH24, CDH11, CDH13, CDH18, CDH8, CDH12, CDH2, CDH5
ParalogsCDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, CDH19, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH5, CDH2
Tissuecerebellum, cerebellar.hemisphere
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000250};
Single-pass type I membrane protein {ECO:0000250}.
Mouse PG classificationNA
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