| Gene Information | |
|---|---|
| Gene Name | CDH19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3298 |
| Protein Names | Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000071991 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | DCHS1 |
| Uniprot ID | Q96JQ0 |
| Pfam | PF00028 |
| In ASD | no |
| Allosteric Prediction | no (-1.325910561) |
| Ortholog in Animals | Alpaca_ CDH19 ( ortholog_one2one ) Dog_ CDH19 ( ortholog_one2one ) GuineaPig_ CDH19 ( ortholog_one2one ) Macaque_ CDH19 ( ortholog_one2one ) Mouse_ Cdh19 ( ortholog_one2one ) Pig_ CDH19 ( ortholog_one2one ) Rat_ Cdh19 ( ortholog_one2one ) Rabbit_ CDH19 ( ortholog_one2one ) |
| Ohnologs | CDH22, CDH2, CDH4, CDH1, CDH3, CDH24, CDH11, CDH13, CDH8, CDH5 |
| Paralogs | CDH7, CDH9, CDH20, CDH4, CDH18, PCDH1, PCDH20, CDH26, PCDH9, CDH3, PCDH11Y, PCDH11X, CDH17, CDHR5, CDHR3, DCHS2, CDH24, CDH23, PCDH7, CDH15, CDHR1, DCHS1, CDH11, CDH8, CDH10, CDH12, CDH13, CDH6, CDH1, CDHR2, CDH22, CDH5, CDH2 |
| Tissue | tibial.nerve |
| Tissue Specificity | Expressed in fibroblasts but not in melanocytes or keratinocytes. {ECO:0000269|PubMed:9199196}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs145099391 rs148882462 rs4758443 rs56920123 rs768737101 rs7924553 rs2659875 rs483352919 rs201457110 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In the embryonic cortex, FAT4 and DCHS1 accumulated at the cell-cell boundaries located apical to the adherens junction. {ECO:0000250}. |
| Mouse PG classification | NA |
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