| Gene Information | |
|---|---|
| Gene Name | ELF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 619 |
| Protein Names | ETS-related transcription factor Elf-1 (E74-like factor 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000120690 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P32519 |
| Gene Card | ELF1 |
| Uniprot ID | P32519 |
| Pfam | PF12310; PF00178 |
| In ASD | no |
| Allosteric Prediction | no (-0.174012477) |
| Ortholog in Animals | Alpaca_ ELF1 ( ortholog_one2one ) Dog_ ELF1 ( ortholog_one2one ) GuineaPig_ ELF1 ( ortholog_one2one ) Macaque_ ELF1 ( ortholog_one2one ) Mouse_ Elf1 ( ortholog_one2one ) Pig_ ELF1 ( ortholog_one2one ) Rat_ Elf1 ( ortholog_one2one ) Rabbit_ ELF1 ( ortholog_one2one ) |
| Ohnologs | ELF4, ELF2 |
| Paralogs | ELK1, ETV6, ERG, ERF, ETV4, ETV7, ELF4, ELF3, EHF, ETV2, ETV3L, ETS2, FLI1, GABPA, ETV5, ETV1, ELF5, ETV3, ELK3, ETS1, ELF2, SPI1, ELK4, SPIB, FEV, SPIC, ERFL, SPDEF |
| Tissue | NA |
| Tissue Specificity | In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. {ECO:0000269|PubMed:8756667, ECO:0000269|PubMed:9524226}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7799 rs1056820 rs7323148 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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