| Gene Information | |
|---|---|
| Gene Name | RXRG |
| Organism | Homo sapiens (Human) |
| Gene Length | 463 |
| Protein Names | Retinoic acid receptor RXR-gamma (Nuclear receptor subfamily 2 group B member 3) (Retinoid X receptor gamma) |
| Target Name | retinoic acid receptor rxr-gamma |
| Target Type | Successful target |
| Gene Age | 987 ( ENSG00000143171 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P48443 |
| Gene Card | RXRG |
| Uniprot ID | P48443 |
| Pfam | PF00104; PF11825; PF00105 |
| In ASD | no |
| Allosteric Prediction | yes (0.664352785) |
| Ortholog in Animals | Alpaca_ RXRG ( ortholog_one2one ) Dog_ RXRG ( ortholog_one2one ) GuineaPig_ RXRG ( ortholog_one2one ) Macaque_ RXRG ( ortholog_one2one ) Mouse_ Rxrg ( ortholog_one2one ) Pig_ RXRG ( ortholog_one2one ) Rat_ Rxrg ( ortholog_one2one ) Rabbit_ RXRG ( ortholog_one2one ) |
| Ohnologs | RXRA, RXRB |
| Paralogs | RXRB, NR2E3, NR2F2, RXRA, HNF4A, NR2F6, HNF4G, NR2C2, NR2C1, NR2F1, NR2E1 |
| Tissue | skeletal.muscle, pituitary.gland |
| Tissue Specificity | Expressed in aortic endothelial cells (at protein level). {ECO:0000269|PubMed:28167758}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003990(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2GL8 (X-ray 2.40A ) 7A79 (X-ray 2.05A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:28167758}. Cytoplasm {ECO:0000269|PubMed:28167758}. |
| Mouse PG classification | NA |
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