| Gene Information | |
|---|---|
| Gene Name | CDCA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1023 |
| Protein Names | Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000184661 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q69YH5 |
| Gene Card | CDCA2 |
| Uniprot ID | Q69YH5 |
| Pfam | PF15276 |
| In ASD | no |
| Allosteric Prediction | no (-0.045883554) |
| Ortholog in Animals | Alpaca_ CDCA2 ( ortholog_one2one ) Dog_ CDCA2 ( ortholog_one2one ) GuineaPig_ CDCA2 ( ortholog_one2one ) Macaque_ CDCA2 ( ortholog_one2one ) Mouse_ Cdca2 ( ortholog_one2one ) Pig_ CDCA2 ( ortholog_one2one ) Rat_ Cdca2 ( ortholog_one2one ) Rabbit_ CDCA2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MKI67 |
| Tissue | testis |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:16492807}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5INB (X-ray 1.30A ) 5IOH (X-ray 2.57A ) 5SW9 (X-ray 2.85A ) |
| DBSNP | rs4872318 rs3829009 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16492807}. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin. |
| Mouse PG classification | NA |
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