| Gene Information | |
|---|---|
| Gene Name | CDC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000094804 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99741 |
| Gene Card | CDC6 |
| Uniprot ID | Q99741 |
| Pfam | PF13401; PF17872; PF09079 |
| In ASD | no |
| Allosteric Prediction | yes (0.042542804) |
| Ortholog in Animals | Alpaca_ CDC6 ( ortholog_one2one ) Dog_ CDC6 ( ortholog_one2one ) GuineaPig_ CDC6 ( ortholog_one2one ) Macaque_ CDC6 ( ortholog_one2one ) Mouse_ Cdc6 ( ortholog_one2one ) Pig_ CDC6 ( ortholog_one2one ) Rat_ Cdc6 ( ortholog_one2one ) Rabbit_ CDC6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ORC1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.068604(Chimpanzee);0.068192(Mouse);0.135837(Rat);0.129255(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2CCH (X-ray 1.70A ) 2CCI (X-ray 2.70A ) 4I5L (X-ray 2.43A ) 4I5N (X-ray 2.80A ) |
| DBSNP | rs4135010 rs4135012 rs4135013 rs387906842 rs4135016 rs13706 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26818844, ECO:0000269|PubMed:9566895}. Cytoplasm {ECO:0000269|PubMed:9566895}. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895). {ECO:0000269|PubMed:9566895}. |
| Mouse PG classification | NA |
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