| Gene Information | |
|---|---|
| Gene Name | RGS20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Regulator of G-protein signaling 20 (RGS20) (Gz-selective GTPase-activating protein) (G(z)GAP) (Gz-GAP) (Regulator of G-protein signaling Z1) (Regulator of Gz-selective protein signaling 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000147509 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O76081 |
| Gene Card | RGS20 |
| Uniprot ID | O76081 |
| Pfam | PF00615 |
| In ASD | no |
| Allosteric Prediction | no (-0.152025923) |
| Ortholog in Animals | Alpaca_ RGS20 ( ortholog_one2one ) Dog_ RGS20 ( ortholog_one2one ) Macaque_ RGS20 ( ortholog_one2one ) Mouse_ Rgs20 ( ortholog_one2one ) Pig_ RGS20 ( ortholog_one2one ) Rat_ Rgs20 ( ortholog_one2one ) |
| Ohnologs | RGS19, RGS17 |
| Paralogs | RGS18, RGS5, RGS3, RGS2, RGSL1, RGS12, RGS21, AXIN1, RGS1, RGS11, RGS17, RGS7, RGS14, AXIN2, RGS22, RGS4, RGS6, RGS9, RGS13, RGS19, RGS8, RGS16, RGS10 |
| Tissue | amygdala, caudate.nucleus, cerebral.cortex, nucleus.accumbens, putamen |
| Tissue Specificity | Isoform 5 is expressed in brain at high levels in the caudate nucleus and temporal lobe. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane; Lipid-anchor. Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm/cell membrane and the nucleus. Anchored to the membrane through palmitoylation. {ECO:0000250}. |
| Mouse PG classification | NA |
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