| Gene Information | |
|---|---|
| Gene Name | CDC42EP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 210 |
| Protein Names | Cdc42 effector protein 2 (Binder of Rho GTPases 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000149798 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O14613 |
| Gene Card | CDC42EP2 |
| Uniprot ID | O14613 |
| Pfam | PF14957; PF00786 |
| In ASD | no |
| Allosteric Prediction | no (-1.282693177) |
| Ortholog in Animals | Alpaca_ CDC42EP2 ( ortholog_one2one ) Dog_ CDC42EP2 ( ortholog_one2one ) GuineaPig_ CDC42EP2 ( ortholog_one2one ) Mouse_ Cdc42ep2 ( ortholog_one2one ) Pig_ CDC42EP2 ( ortholog_one2one ) Rat_ Cdc42ep2 ( ortholog_one2one ) Rabbit_ CDC42EP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CDC42EP5, C15orf62, CDC42EP1, CDC42EP3, CDC42EP4 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the heart. Weakly expressed in the pancreas and liver. {ECO:0000269|PubMed:10490598}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4149839 rs7120634 |
| Subcellular location [CC] | Endomembrane system {ECO:0000269|PubMed:11035016}; Peripheral membrane protein {ECO:0000269|PubMed:11035016}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11035016}. |
| Mouse PG classification | NA |
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