| Gene Information | |
|---|---|
| Gene Name | KIAA0167 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1192 |
| Protein Names | Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (GTP-binding and GTPase-activating protein 2) (GGAP2) (Phosphatidylinositol 3-kinase enhancer) (PIKE) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q99490 |
| Gene Card | AGAP2 |
| Uniprot ID | Q99490 |
| Pfam | PF12796; PF01412; PF00071 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Isoform 1 is brain-specific. Isoform 2 is ubiquitously expressed, with highest levels in brain and heart. {ECO:0000269|PubMed:12640130, ECO:0000269|PubMed:14761976, ECO:0000269|PubMed:15118108, ECO:0000269|PubMed:16079295, ECO:0000269|PubMed:16150119}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2BMJ (X-ray 2.10A ) 2IWR (X-ray 1.50A ) 2RLO (NMR - ) |
| DBSNP | rs2301553 rs238521 |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm. Nucleus.; [Isoform 2]: Cytoplasm. |
| Mouse PG classification | NA |
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