| Gene Information | |
|---|---|
| Gene Name | FREM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2179 |
| Protein Names | FRAS1-related extracellular matrix protein 1 (Protein QBRICK) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000164946 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q5H8C1 |
| Gene Card | FREM1 |
| Uniprot ID | Q5H8C1 |
| Pfam | PF03160; PF19309; PF00059 |
| In ASD | no |
| Allosteric Prediction | no (-1.268998497) |
| Ortholog in Animals | Alpaca_ FREM1 ( ortholog_one2one ) Dog_ FREM1 ( ortholog_one2one ) GuineaPig_ FREM1 ( ortholog_one2one ) Macaque_ FREM1 ( ortholog_one2one ) Mouse_ Frem1 ( ortholog_one2one ) Pig_ FREM1 ( ortholog_one2one ) Rat_ Frem1 ( ortholog_one2one ) Rabbit_ FREM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FREM3, FREM2, FRAS1, SLC8A1, SLC8A3, SLC8A2, ADGRV1 |
| Tissue | endometrium, kidney, smooth.muscle |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1338652795 rs2779500 rs184394424 rs1353223 rs121912609 rs7023244 rs7041710 rs16932300 rs7025814 rs281875281 rs121912610 rs281875280 rs10961700 rs2101770 rs281875282 rs10961689 rs17856912 |
| Subcellular location [CC] | Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250|UniProtKB:Q684R7}. Note=Localizes at the basement membrane zone of embryonic epidermis and hair follicles. {ECO:0000250|UniProtKB:Q684R7}. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |