| Gene Information | |
|---|---|
| Gene Name | SLC8A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 921 |
| Protein Names | Sodium/calcium exchanger 2 (Na(+)/Ca(2+)-exchange protein 2) (Solute carrier family 8 member 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000118160 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UPR5 |
| Gene Card | SLC8A2 |
| Uniprot ID | Q9UPR5 |
| Pfam | PF03160; PF01699; PF16494 |
| In ASD | no |
| Allosteric Prediction | no (-0.048567826) |
| Ortholog in Animals | Alpaca_ SLC8A2 ( ortholog_one2one ) Dog_ SLC8A2 ( ortholog_one2one ) GuineaPig_ SLC8A2 ( ortholog_one2one ) Macaque_ SLC8A2 ( ortholog_one2one ) Mouse_ Slc8a2 ( ortholog_one2one ) Pig_ SLC8A2 ( ortholog_one2one ) Rat_ Slc8a2 ( ortholog_one2one ) |
| Ohnologs | SLC8A3, SLC8A1 |
| Paralogs | FREM3, FREM2, FRAS1, SLC8A1, FREM1, SLC8A3, ADGRV1 |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs201723439 rs17759929 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P48768}; Multi-pass membrane protein {ECO:0000250|UniProtKB:P48768}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8K596}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q8K596}. Perikaryon {ECO:0000250|UniProtKB:P48768}. Cell projection, dendrite {ECO:0000250|UniProtKB:P48768}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:P48768}. |
| Mouse PG classification | NA |
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