| Gene Information | |
|---|---|
| Gene Name | CREB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 327 |
| Protein Names | Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1) |
| Target Name | cyclic amp-responsive element-binding protein 1 |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000118260 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P16220 |
| Gene Card | CREB1 |
| Uniprot ID | P16220 |
| Pfam | PF00170; PF02173 |
| In ASD | no |
| Allosteric Prediction | yes (0.754011249) |
| Ortholog in Animals | Alpaca_ CREB1 ( ortholog_one2one ) Dog_ CREB1 ( ortholog_one2one ) GuineaPig_ CREB1 ( ortholog_one2one ) Macaque_ CREB1 ( ortholog_one2one ) Mouse_ Creb1 ( ortholog_one2one ) Pig_ CREB1 ( ortholog_one2one ) Rat_ Creb1 ( ortholog_one2many ) Rat_ AABR07031674.2 ( ortholog_one2many ) Rabbit_ CREB1 ( ortholog_one2one ) |
| Ohnologs | CREM, ATF1 |
| Paralogs | CREB3L2, CREB3L3, ATF6, ATF1, ATF6B, CREB3L4, CREB3L1, CREM, CREB3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001731(Rat);0.032(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LXT (NMR - ) 5ZK1 (X-ray 3.05A ) 5ZKO (X-ray 3.05A ) |
| DBSNP | rs387906617 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00312, ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12552083}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |