| Gene Information | |
|---|---|
| Gene Name | CD96 |
| Organism | Homo sapiens (Human) |
| Gene Length | 585 |
| Protein Names | T-cell surface protein tactile (Cell surface antigen CD96) (T cell-activated increased late expression protein) (CD antigen CD96) |
| Target Name | t-cell surface protein tactile |
| Target Type | Clinical trial target |
| Gene Age | 132 ( ENSG00000153283 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P40200 |
| Gene Card | CD96 |
| Uniprot ID | P40200 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.220076309) |
| Ortholog in Animals | Alpaca_ CD96 ( ortholog_one2one ) Dog_ CD96 ( ortholog_one2one ) GuineaPig_ CD96 ( ortholog_one2one ) Macaque_ CD96 ( ortholog_one2one ) Mouse_ Cd96 ( ortholog_one2one ) Pig_ CD96 ( ortholog_one2one ) Rat_ Cd96 ( ortholog_one2one ) Rabbit_ CD96 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed on normal T-cell lines and clones, and some transformed T-cells, but no other cultured cell lines tested. It is expressed at very low levels on activated B-cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ARQ (X-ray 2.88A ) |
| DBSNP | rs2276872 rs119477056 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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