| Gene Information | |
|---|---|
| Gene Name | KLC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 504 |
| Protein Names | Kinesin light chain 3 (KLC2-like) (kinesin light chain 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000174996 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q6P597 |
| Gene Card | KLC3 |
| Uniprot ID | Q6P597 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.338667709) |
| Ortholog in Animals | Alpaca_ KLC2 ( ortholog_one2one ) GuineaPig_ KLC2 ( ortholog_one2one ) Macaque_ KLC2 ( ortholog_one2one ) Mouse_ Klc2 ( ortholog_one2one ) Pig_ KLC2 ( ortholog_one2one ) Rat_ Klc2 ( ortholog_one2one ) |
| Ohnologs | KLC3, KLC1, KLC4 |
| Paralogs | KLC1, APPBP2, KLC3, NPHP3, KLC4 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q68G30, ECO:0000250|UniProtKB:Q91W40}. Mitochondrion {ECO:0000250|UniProtKB:Q91W40}. Note=In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids. {ECO:0000250|UniProtKB:Q68G30, ECO:0000250|UniProtKB:Q91W40}. |
| Mouse PG classification | NA |
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