| Gene Information | |
|---|---|
| Gene Name | MNDA |
| Organism | Homo sapiens (Human) |
| Gene Length | 407 |
| Protein Names | Myeloid cell nuclear differentiation antigen |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 168 ( ENSG00000163563 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P41218 |
| Gene Card | MNDA |
| Uniprot ID | P41218 |
| Pfam | PF02760; PF02758 |
| In ASD | no |
| Allosteric Prediction | yes (0.07680301) |
| Ortholog in Animals | Alpaca_ MNDA ( ortholog_one2one ) Pig_ MNDA ( ortholog_one2one ) Rabbit_ MNDA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFI16, PYHIN1, AIM2 |
| Tissue | whole.blood |
| Tissue Specificity | Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appears in myeloblast cells in some cases of acute myeloid Leukemia. {ECO:0000269|PubMed:8175894}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DBG (NMR - ) 5H7Q (X-ray 1.45A ) 5WPZ (X-ray 2.00A ) |
| DBSNP | rs35417083 rs1056771 rs2276403 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Note=Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin. |
| Mouse PG classification | NA |
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