| Gene Information | |
|---|---|
| Gene Name | CD79A |
| Organism | Homo sapiens (Human) |
| Gene Length | 226 |
| Protein Names | B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000105369 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P11912 |
| Gene Card | CD79A |
| Uniprot ID | P11912 |
| Pfam | PF00047; PF02189 |
| In ASD | no |
| Allosteric Prediction | no (-0.623018706) |
| Ortholog in Animals | Alpaca_ CD79A ( ortholog_one2one ) Dog_ CD79A ( ortholog_one2one ) GuineaPig_ CD79A ( ortholog_one2one ) Macaque_ CD79A ( ortholog_one2one ) Mouse_ Cd79a ( ortholog_one2one ) Pig_ CD79A ( ortholog_one2one ) Rat_ Cd79a ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD79B |
| Tissue | appendix, lymph.node, spleen |
| Tissue Specificity | B-cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CV9 (NMR - ) 7WSO (EM 3.03A ) 7XQ8 (EM 3.30A ) 7XT6 (EM 3.63A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. {ECO:0000250}. |
| Mouse PG classification | LPG |
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