| Gene Information | |
|---|---|
| Gene Name | TNFSF18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 177 |
| Protein Names | Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000120337 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9UNG2 |
| Gene Card | TNFSF18 |
| Uniprot ID | Q9UNG2 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.940555319) |
| Ortholog in Animals | Alpaca_ TNFSF18 ( ortholog_one2one ) Dog_ TNLG2A ( ortholog_one2one ) GuineaPig_ TNFSF18 ( ortholog_one2one ) Macaque_ TNFSF18 ( ortholog_one2one ) Mouse_ Tnfsf18 ( ortholog_one2one ) Pig_ TNFSF18 ( ortholog_one2one ) Rat_ Tnfsf18 ( ortholog_one2one ) Rabbit_ TNFSF18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2Q1M (X-ray 2.30A ) 2R30 (X-ray 3.20A ) 2R32 (X-ray 1.95A ) 3B93 (X-ray 2.20A ) 3B94 (X-ray 2.50A ) 7KHD (X-ray 2.96A ) 7LAW (X-ray 2.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17449724}; Single-pass type II membrane protein {ECO:0000269|PubMed:17449724}. |
| Mouse PG classification | NA |
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