| Gene Information | |
|---|---|
| Gene Name | CD5L |
| Organism | Homo sapiens (Human) |
| Gene Length | 347 |
| Protein Names | CD5 antigen-like (Apoptosis inhibitor expressed by macrophages) (hAIM) (CT-2) (IgM-associated peptide) (SP-alpha) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000073754 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O43866 |
| Gene Card | CD5L |
| Uniprot ID | O43866 |
| Pfam | PF00530 |
| In ASD | no |
| Allosteric Prediction | no (-0.698481067) |
| Ortholog in Animals | Alpaca_ CD5L ( ortholog_one2one ) Dog_ CD5L ( ortholog_one2one ) GuineaPig_ CD5L ( ortholog_one2one ) Macaque_ CD5L ( ortholog_one2one ) Mouse_ Cd5l ( ortholog_one2one ) Rat_ Cd5l ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD6, LOX, SSC4D, SSC5D, LGALS3BP, LOXL4, SCART1, CD163, PRSS12, DMBT1, LOXL3, CD5, LOXL1, LOXL2, CD163L1 |
| Tissue | spleen |
| Tissue Specificity | Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues. {ECO:0000269|PubMed:9045627}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11537583 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:24223991, ECO:0000269|PubMed:24804991}. Cytoplasm {ECO:0000250|UniProtKB:Q9QWK4}. Note=Secreted by macrophages and circulates in the blood (PubMed:24223991, PubMed:24804991). Transported in the cytoplasm via CD36-mediated endocytosis (By similarity). {ECO:0000250|UniProtKB:Q9QWK4, ECO:0000269|PubMed:24223991, ECO:0000269|PubMed:24804991}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |