| Gene Information | |
|---|---|
| Gene Name | CD59 |
| Organism | Homo sapiens (Human) |
| Gene Length | 128 |
| Protein Names | CD59 glycoprotein (1F5 antigen) (20 kDa homologous restriction factor) (HRF-20) (HRF20) (MAC-inhibitory protein) (MAC-IP) (MEM43 antigen) (Membrane attack complex inhibition factor) (MACIF) (Membrane inhibitor of reactive lysis) (MIRL) (Protectin) (CD antigen CD59) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000085063 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P13987 |
| Gene Card | CD59 |
| Uniprot ID | P13987 |
| Pfam | PF00021 |
| In ASD | no |
| Allosteric Prediction | yes (0.093483966) |
| Ortholog in Animals | Dog_ CD59 ( ortholog_one2one ) Mouse_ Cd59a ( ortholog_one2many ) Mouse_ Cd59b ( ortholog_one2many ) Rat_ Cd59 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LYPD1, SLURP1, LYPD2 |
| Tissue | placenta |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1CDQ (NMR - ) 1CDR (NMR - ) 1CDS (NMR - ) 1ERG (NMR - ) 1ERH (NMR - ) 2J8B (X-ray 1.15A ) 2OFS (X-ray 2.12A ) 2UWR (X-ray 1.34A ) 2UX2 (X-ray 1.80A ) 4BIK (X-ray 3.49A ) 5IMT (X-ray 2.70A ) 5IMY (X-ray 2.40A ) 6ZD0 (EM 4.60A ) |
| DBSNP | rs397514767 |
| Subcellular location [CC] | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Soluble form found in a number of tissues. |
| Mouse PG classification | NA |
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