| Gene Information | |
|---|---|
| Gene Name | ICAM1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Intercellular adhesion molecule 1 (ICAM-1) (Major group rhinovirus receptor) (CD antigen CD54) |
| Target Name | icam1 messenger rna |
| Target Type | Successful target |
| Gene Age | 132 ( ENSG00000090339 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P05362 |
| Gene Card | ICAM1 |
| Uniprot ID | P05362 |
| Pfam | PF03921 |
| In ASD | no |
| Allosteric Prediction | yes (0.960487513) |
| Ortholog in Animals | Alpaca_ ICAM1 ( ortholog_one2one ) Dog_ ICAM1 ( ortholog_one2one ) Macaque_ ICAM1 ( ortholog_one2one ) Mouse_ Icam1 ( ortholog_one2one ) Pig_ ICAM1 ( ortholog_one2one ) Rat_ Icam1 ( ortholog_one2one ) Rabbit_ ICAM1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ICAM2, ICAM3, ICAM4, ICAM5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002101(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1D3E (EM 28.00A ) 1D3I (EM 26.00A ) 1D3L (X-ray 3.25A ) 1IAM (X-ray 2.10A ) 1IC1 (X-ray 3.00A ) 1MQ8 (X-ray 3.30A ) 1P53 (X-ray 3.06A ) 1Z7Z (EM 8.00A ) 2OZ4 (X-ray 2.70A ) 3TCX (X-ray 3.60A ) 5MZA (X-ray 2.78A ) 6EIT (EM 3.90A ) 6S8U (X-ray 3.67A ) 7BG7 (EM 2.40A ) |
| DBSNP | rs5491 rs5492 rs1799969 rs5495 rs1801714 rs5497 rs5498 rs5030400 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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