| Gene Information | |
|---|---|
| Gene Name | CALU |
| Organism | Homo sapiens (Human) |
| Gene Length | 315 |
| Protein Names | Calumenin (Crocalbin) (IEF SSP 9302) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000128595 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43852 |
| Gene Card | CALU |
| Uniprot ID | O43852 |
| Pfam | PF13202; PF13833 |
| In ASD | no |
| Allosteric Prediction | yes (0.143518669) |
| Ortholog in Animals | Alpaca_ CALU ( ortholog_one2one ) Dog_ CALU ( ortholog_one2one ) GuineaPig_ CALU ( ortholog_one2one ) Macaque_ CALU ( ortholog_one2one ) Mouse_ Calu ( ortholog_one2one ) Pig_ CALU ( ortholog_one2one ) Rat_ Calu ( ortholog_one2one ) Rabbit_ CALU ( ortholog_one2one ) |
| Ohnologs | RCN1, RCN3 |
| Paralogs | RCN1, RCN3, SDF4, RCN2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed at high levels in heart, placenta and skeletal muscle, at lower levels in lung, kidney and pancreas and at very low levels in brain and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2290228 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:10222138}. Golgi apparatus {ECO:0000269|PubMed:10222138}. Secreted {ECO:0000305}. Melanosome {ECO:0000269|PubMed:12643545}. Sarcoplasmic reticulum lumen {ECO:0000305}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. {ECO:0000269|PubMed:12643545}. |
| Mouse PG classification | NA |
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