| Gene Information | |
|---|---|
| Gene Name | CD3G |
| Organism | Homo sapiens (Human) |
| Gene Length | 182 |
| Protein Names | T-cell surface glycoprotein CD3 gamma chain (T-cell receptor T3 gamma chain) (CD antigen CD3g) |
| Target Name | t-cell surface glycoprotein cd3 gamma chain |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000160654 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P09693 |
| Gene Card | CD3G |
| Uniprot ID | P09693 |
| Pfam | PF16680; PF02189 |
| In ASD | no |
| Allosteric Prediction | yes (0.363036349) |
| Ortholog in Animals | Alpaca_ CD3G ( ortholog_one2one ) Dog_ CD3G ( ortholog_one2one ) GuineaPig_ CD3G ( ortholog_one2one ) Macaque_ CD3G ( ortholog_one2one ) Mouse_ Cd3g ( ortholog_one2one ) Rat_ Cd3g ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD3D, CD3E |
| Tissue | lymph.node, tonsil, appendix, spleen |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.080033(Rat);0.040000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1SY6 (X-ray 2.10A ) 6JXR (EM 3.70A ) 7FJD (EM 3.20A ) 7FJE (EM 3.00A ) 7FJF (EM 3.10A ) 7PHR (EM 3.08A ) 7Q5U (X-ray 2.40A ) |
| DBSNP | rs3753058 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:8636209}; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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