| Gene Information | |
|---|---|
| Gene Name | CD3E |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e) |
| Target Name | t-cell surface glycoprotein cd3 epsilon |
| Target Type | Successful target |
| Gene Age | 454 ( ENSG00000198851 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P07766 |
| Gene Card | CD3E |
| Uniprot ID | P07766 |
| Pfam | PF02189 |
| In ASD | no |
| Allosteric Prediction | yes (0.189356963) |
| Ortholog in Animals | Alpaca_ CD3E ( ortholog_one2one ) GuineaPig_ CD3E ( ortholog_one2one ) Macaque_ CD3E ( ortholog_one2one ) Mouse_ Cd3e ( ortholog_one2one ) Pig_ CD3E ( ortholog_one2one ) Rat_ Cd3e ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CD3D, CD3G |
| Tissue | spleen, whole.blood |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.061538(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1A81 (X-ray 3.00A ) 1SY6 (X-ray 2.10A ) 1XIW (X-ray 1.90A ) 2ROL (NMR - ) 5QU2 (X-ray 1.04A ) 6JXR (EM 3.70A ) 7FJD (EM 3.20A ) 7FJE (EM 3.00A ) 7FJF (EM 3.10A ) 7PHR (EM 3.08A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10384095, ECO:0000269|PubMed:15294938}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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