Gene Information
Gene NameOSGEPL1
OrganismHomo sapiens (Human)
Gene Length414
Protein NamestRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial (EC 2.3.1.234) (N6-L-threonylcarbamoyladenine synthase) (t(6)A synthase) (O-sialoglycoprotein endopeptidase-like protein 1) (OSGEP-like protein 1) (t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1) (tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000128694 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ9H4B0
Gene CardOSGEPL1
Uniprot IDQ9H4B0
PfamPF00814
In ASDno
Allosteric Predictionno (-1.207962005)
Ortholog in AnimalsAlpaca_ OSGEPL1 ( ortholog_one2one )
Dog_ OSGEPL1 ( ortholog_one2one )
GuineaPig_ OSGEPL1 ( ortholog_one2one )
Macaque_ OSGEPL1 ( ortholog_one2one )
Mouse_ Osgepl1 ( ortholog_one2one )
Pig_ OSGEPL1 ( ortholog_one2one )
Rat_ Osgepl1 ( ortholog_one2one )
Rabbit_ OSGEPL1 ( ortholog_one2one )
OhnologsNA
ParalogsOSGEP
TissueNA
Tissue SpecificityWidely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus. {ECO:0000269|PubMed:19694617}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs3749014 
Subcellular location [CC]Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03179, ECO:0000269|PubMed:19694617, ECO:0000269|PubMed:29760464}.
Mouse PG classificationNA
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