| Gene Information | |
|---|---|
| Gene Name | CD320 |
| Organism | Homo sapiens (Human) |
| Gene Length | 282 |
| Protein Names | CD320 antigen (8D6 antigen) (FDC-signaling molecule 8D6) (FDC-SM-8D6) (Transcobalamin receptor) (TCblR) (CD antigen CD320) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000167775 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9NPF0 |
| Gene Card | CD320 |
| Uniprot ID | Q9NPF0 |
| Pfam | PF00057 |
| In ASD | no |
| Allosteric Prediction | no (-0.18948744) |
| Ortholog in Animals | Alpaca_ CD320 ( ortholog_one2one ) Dog_ CD320 ( ortholog_one2one ) GuineaPig_ CD320 ( ortholog_one2one ) Macaque_ CD320 ( ortholog_one2one ) Mouse_ Cd320 ( ortholog_one2one ) Pig_ CD320 ( ortholog_one2one ) Rat_ Ndufa7 ( ortholog_one2one ) Rabbit_ CD320 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LDLRAD2 |
| Tissue | NA |
| Tissue Specificity | Detected in the germinal center (GC) of lymphoid follicles (at protein level) (PubMed:11418631). Expressed abundantly on follicular dendritic cells (FDCs) (PubMed:10727470). {ECO:0000269|PubMed:10727470, ECO:0000269|PubMed:11418631}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4ZRP (X-ray 2.10A ) 4ZRQ (X-ray 2.60A ) 7QBD (X-ray 4.18A ) 7QBE (X-ray 3.00A ) 7QBF (X-ray 1.85A ) 7QBG (X-ray 2.69A ) |
| DBSNP | rs2232775 rs150384171 rs2336573 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10727470, ECO:0000269|PubMed:11418631, ECO:0000305|PubMed:18779389}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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