| Gene Information | |
|---|---|
| Gene Name | GREM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 168 |
| Protein Names | Gremlin-2 (Cysteine knot superfamily 1, BMP antagonist 2) (DAN domain family member 3) (Protein related to DAN and cerberus) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000180875 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9H772 |
| Gene Card | GREM2 |
| Uniprot ID | Q9H772 |
| Pfam | PF03045 |
| In ASD | no |
| Allosteric Prediction | no (-1.791614966) |
| Ortholog in Animals | Alpaca_ GREM2 ( ortholog_one2one ) Dog_ GREM2 ( ortholog_one2one ) GuineaPig_ GREM2 ( ortholog_one2one ) Macaque_ GREM2 ( ortholog_one2one ) Mouse_ Grem2 ( ortholog_one2one ) Pig_ GREM2 ( ortholog_one2one ) Rat_ Grem2 ( ortholog_one2one ) Rabbit_ GREM2 ( ortholog_one2one ) |
| Ohnologs | GREM1 |
| Paralogs | GREM1, NBL1 |
| Tissue | liver, ovary, sigmoid.colon |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.2(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs373941682 rs142343894 rs34188522 rs1057519288 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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